Presented at: AACR 2022
Improved Understanding of the Biology and Pathophysiology of the TME in PDAC Samples Revealed by Both InSituPlex and Imaging Mass Cytometry
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Collaboration, FixVUE, Imaging mass cytometry, InSituPlex
Description This poster demonstrates a unique tissue phenotyping workflow combining three complementary methods that can unravel novel insights in the complex tumor microenvironment. The highlighted workflow delivers tissue morphology information, spatial phenotyping of immune cell population on whole slides, and high-dimensional imaging in selected regions of interest (ROIs) by combining H&E, multiplex immunofluorescence (mIF), and Imaging Mass Cytometry™(IMC™) together with bespoke data analysis.
Andrew Quong, Nina Lane, Derek Quong, Gourab Chatterjee, Devan Fleury, Kirsteen H. Maclean, Maël Manesse, Keith A. Wharton Jr, Fabian Schneider, Dan Winkowski and James Mansfield.