Publications
Please see below for a list of peer-reviewed publications highlighting how InSituPlex technology is furthering research in oncology.
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Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival
Singhal, S.K., Byun, J.S., Park, S. et al. Kaiso
Commun Biol 4, 150 (2021); https://doi.org/10.1038/s42003-021-01651-y
Intratumoral Combinatorial Administration of CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Ipilimumab and Avelumab in Combination with Intravenous Low-Dose Nivolumab in Patients with Advanced Solid Tumors: A Phase IB Clinical Trial
Schwarze, J. K., Awada, G., Cras, L., Tijtgat, J., Forsyth, R., Dufait, I., Tuyaerts, S., Van Riet, I., & Neyns, B.
Vaccines 8(4), 670; https://doi.org/10.3390/vaccines8040670
Improving the Diagnostic Accuracy of the PD-L1 Test with Image Analysis and Multiplex Hybridization
Humphries, M.P.; Bingham, V.; Abdullahi Sidi, F.; Craig, S.G.; McQuaid, S.; James, J.; Salto-Tellez, M.
Cancers 2020, 12(5), 1114; https://doi.org/10.3390/cancers12051114
Overview of multiplex immunohistochemistry / immunofluorescence techniques in the era of cancer immunotherapy
Tan WCC, Nerurkar SN, Cai HY, et al.
Cancer Communications. 2020;40:135–153. https://doi.org/10.1002/cac2.12023
Single-Cell Genomic Characterization Reveals the Cellular Reprogramming of the Gastric Tumor Microenvironment
Anuja Sathe, Susan M. Grimes, Billy T. Lau, Jiamin Chen, Carlos Suarez, Robert J. Huang, George Poultsides and Hanlee P. Ji
Clin Cancer Res 2020;26:2640–53 https://doi.org/10.1158/1078-0432.CCR-19-3231
The coming 15 years in gynaecological pathology: digitisation, artificial intelligence, and new technologies
Farnell DA, Huntsman D, Bashashati A.
Histopathology 2020, 76, 171–177. https://doi.org/10.1111/his.13991
New Technologies to Image Tumors
McNamara G. et al.
(2020) New Technologies to Image Tumors. In: Lee P., Marincola F. (eds) Tumor Microenvironment. Cancer Treatment and Research, vol 180. Springer, Cham. https://doi.org/10.1007/978-3-030-38862-1_2
Multiplexed immunohistochemistry for immune cell phenotyping, quantification and spatial distribution in situ
Vasaturo A, Galon J.
Methods in Enzymology 2020; 635, 51-66 https://doi.org/10.1016/bs.mie.2019.10.002
Biomarkers for Immunotherapy of Cancer
Thurin, M., Cesano, A., & Marincola, F. M. (Eds.).
(2020). Biomarkers for Immunotherapy of Cancer. Methods in Molecular Biology. doi:10.1007/978-1-4939-9773-2
PD-L1 Protein Expression on Both Tumor Cells and Macrophages are Associated with Response to Neoadjuvant Durvalumab with Chemotherapy in Triple-negative Breast Cancer
Fahad Shabbir Ahmed, Patricia Gaule, John McGuire, Katir Patel, Kim Blenman, Lajos Pusztai and David L. Rimm
Clin Cancer Res August 25 2020 DOI: 10.1158/1078-0432.CCR-20-1303
