UltiMapper I/O PD-L1
Determine whether the tumor is “hot” or “cold”
Markers: CD8, CD68, PD-L1, panCK/SOX10
Phenotypes:
- Cytotoxic immune cells
- Immunosuppressive macrophages
- Immune evading tumor cells
UltiMapper I/O T-reg
Characterize regulatory T cells and cytotoxic T cells
Markers: CD8, CD4, FoxP3, panCK/SOX10
Phenotypes:
- T helper cells
- Regulatory T cells
- Cytotoxic T cells
UltiMapper I/O MDSC
Profile myeloid-derived suppressor cells
Markers: CD11b, CD14, CD15, HLA-DR
Phenotypes:
- Antigen-presenting cells
- M-MDSCs
- PMN-MDSCs
UltiMapper I/O PD-1
Determine whether the immune response has exhausted
Markers: CD3, CD45RO, PD-1, panCK/SOX10
Phenotypes:
- Exhausted memory cells
- Exhausted T cells
- Exhausted memory T cells
UltiMapper I/O T-act
Determine whether T cells have the potential to mediate cell death
Markers: CD3, Granzyme B, Ki67, panCK/SOX10
Phenotypes:
- Proliferating T cells
- Cytotoxic T cells
- Proliferating tumor cells
UltiMapper I/O APC
Identify and characterize professional antigen-presenting cells (APCs)
Markers: CD11c, CD20, CD68/CD163, MHC II
Phenotypes:
- Dendritic cells
- B cells
- Macrophages
UltiMapper I/O Immuno8
Identify and characterize T-cell subsets, immunosuppressive cells, and interactions along the PD-1/PD-L1 checkpoint axis.
Markers: CD3, CD4, CD8, CD68, FoxP3, PD-1, PD-L1, CK/SOX10
Phenotypes:
- Double-positive T cells
- Regulatory T cells
- Immunosuppressive macrophages
For Research Use Only, not for use in diagnostic procedures
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InSituPlex
Our proprietary InSituPlex technology enables unsurpassed biomarker detection and analysis in tissue, with no compromise on level of multiplexing, throughput of sample staining and imaging, and without requiring dedicated instrumentation.
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Services and Biomarker Programs
With speed and flexibility at heart, our Staining & Imaging services and Biomarker Programs offer highly customizable panels to include all your markers of interest.
Explore our Technology
InSituPlex®
Our proprietary InSituPlex technology enables unsurpassed biomarker detection and analysis in tissue, with no compromise on level of multiplexing, throughput of sample staining and imaging, and without requiring dedicated instrumentation.
Explore our Services
Standard and Custom Services
With speed and flexibility at heart, our Biomarker Programs offer validated 5-Plex in addition to highly customizable panels to include all your markers of interest