Panel Configurator

Ready to get started identifying spatial patterns within whole tissue samples? FixVUE and FlexVUE panels are ready-to-go kits that let you get started quickly and easily. Get unprecedented clarity so you can make the next biomarker discovery, move your project forward, and implement spatial phenomics into your immuno-oncology programs.

FlexVUE

Customized 8-plex panels delivered to your lab. Start with the Immuno8 FixVUE panel and exchange 1 – 2 markers from the list of pre-optimized markers. Create specialized panels to explore the biomarkers that you need.

Configure your own panel

FixVUE

Pre-defined panels sent to you right away. Choose from 4- or 8-plex marker combinations that address the most interesting cell populations in the tissue microenvironment. 

Explore our predefined panels

Create your FlexVUE™ panel

Guide: To create your own panel, exchange any 1 or 2 markers from the menu of pre-optimized markers. Simply drag and drop one of the pre-optimized markers (on the left) onto one of the markers in the default panel. Find descriptions for all markers below. When you are satisfied with your panel, add a name for your selection and then add to the shopping cart.

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Pre-optimized markers
Marker descriptions

Drag and drop a marker from the left on the marker you want to exchange.

CD11b
CD11b
CD11c
CD11c
CD14
CD14
CD15
CD15
CD20
CD20
CD56
CD56
CD45RO
CD45RO
CD163
CD163
CD206
CD206
GrzB
GrzB
HLA-DR
HLA-DR
Ki67
Ki67
MHC II
MHC II
Configure your FlexVUE Panel (You can exchange up to 2 markers.)
CD3
CD3
CD4
CD4
CD8
CD8
CD68
CD68
FoxP3
FoxP3
PD-1
PD-1
PD-L1
PD-L1
CK/SOX10
CK/SOX10

No markers have been exchanged yet

Price: Please log in/register here to get the prices displayed

Create your FlexVUE™ panel

Guide: To create your own panel, exchange any 1 or 2 markers from the menu of pre-optimized markers. Simply drag and drop one of the pre-optimized markers (on the left) onto one of the markers in the default panel. Find descriptions for all markers below. When you are satisfied with your panel, add a name for your selection and then add to the shopping cart.

Pre-optimized markers

Marker descriptions
CD3
CD4
CD8
CD68
FoxP3
PD-1
PD-L1
CK/SOX10

Select the Marker you want to exchange with CD8

CD11b
CD11c
CD14
CD15
CD20
CD56
CD45RO
CD163
CD206
GrzB
HLA-DR
Ki67
MHC II

No markers have been exchanged yet

Price: Please log in/register here to get the prices displayed

Pre-defined FixVUE panels

Choose the pre-configured panel that best suits your research needs. Designed to assess the significant cell markers in the tissue microenvironment, these robust 4 and 8 plex panels are ready to use across multiple indications.

Prices are available from your local representative. Submit your configuration to learn more.

Immuno8 FixVUE Panel

Characterize T-cell subsets, immunosuppressive cells and interactions along the PD-L1/PD-1 checkpoint axis with this comprehensive immuno-oncology focused panel.

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PD-L1 FixVUE Panel

Determine whether the tumor is “hot” or “cold”. Co-localize macrophages, cytotoxic T cells, tumor cells, and the underlying inhibitory or inflammatory mechanisms at play along the PD-L1 axis.

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T-reg FixVUE Panel

Identify regulatory T cells and cytotoxic T cells within the tumor context. Characterize the different T cells that regulate immune response.

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MDSC FixVUE Panel

Identify Myeloid Derived Suppressor Cells within the tumor microenvironment. Characterize cell populations into M-MDSCs and PMN-MDSCs.

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PD-1 FixVUE panel

Determine whether the immune response has exhausted. Co-localize T cells, memory T cells, tumor cells, and the underlying PD-1 checkpoint immune exhaustion mechanism at play.

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T-act FixVUE Panel

Determine whether T cells have the potential to mediate cell death. Examine the co-expression of proliferating cells, cytotoxic cells, tumor cells, and the underlying proliferative index and potential for T cell mediated death.

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APC FixVUE Panel

Identify and characterize professional antigen-presenting cells (APCs). Examine the co-expression and visualization of specific subsets of cells along the dendritic, monocyte/macrophage, and B cell lineages.

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Not sure which panel you need?

Not sure which panel you need?

Talk to an expert

FAQs

What equipment do I need to run a FixVUE or FlexVUE panel in my lab?

All FixVUE and FlexVUE kits are delivered as a complete set of reagents to perform multiplex staining on up to 10 tissue slides per kit. In addition to the typical lab equipment needed to process tissue slides, InSituPlex assays have been optimized for use with the Leica Biosystems BOND RX automated stainer, or via a manual protocol when this autostainer is not available.

In addition, the use of UltiStacker software is recommended to perform same slide image fusion of both multiplex immunofluorescent (mIF) images and H&E images. Once co-registered with this software, the images are ready for use with image analysis software. UltiStacker is available upon request with any FixVUE or FlexVUE order.

For the complete list of requirements, please contact us and we would be happy to set up a consultation with you.

Do I need to optimize the protocol for my tissue samples?

Multiplex assays using InSituPlex technology have been pre-optimized for use across indications, allowing you to eliminate time consuming optimization steps. The FixVUE and FlexVUE kits are ready to use out of the box, simply follow the included protocol to achieve unprecedented resolution across your entire tissue sample.

Find out more about InSituPlex technology here.

The marker I need isn’t listed in the FlexVUE menu; how can I add it?

In addition to FlexVUE and FixVUE marker panels, we offer an extensive list of pre-optimized markers in our U-VUE menu. This fully customizable biomarker menu allows you to build the unique panel to fit your research needs. In addition, our experts are on hand to help you design, build and execute your assays either directly in your lab or through our CLIA certified services lab.

Find out more about U-VUE markers here or contact us to help you get started building your custom panels.

Do you ship to my country?

Currently, ordering through our webshop is only available for organizations in the following countries: Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Luxembourg, Netherlands, Norway, Poland, Portugal, Slovakia, Spain, Sweden, Switzerland, Turkey, United Kingdom, and the United States.

If you are not located in these countries, please contact us here to find out what shipping options may be available to you through our network of distributors.