STARVUE™

Unlock unprecedented insights into the tumor microenvironment and accelerate your breakthroughs with STARVUE™, our intuitive spatial analysis platform.

Talk to Our Spatial Biology Experts

Robust AI-driven spatial insights at scale

  • AI-driven biomarker classification
  • Automated; No manual thresholding
  • Easy-to-use collaborative platform
  • Cloud scalability is 10x – 100x faster
  • Highly customizable phenotyping

Tumor microenvironment studies are hindered by spatial data complexity and constraints.

  1. Large data volumes
    Whole slide multiplex immunofluorescence (mIF) scanning of tissue samples produces an enormous amount of data.
  2. Complex, multi-step workflows
    Reliably processing large data sets often requires manual navigation of complex, multi-program worflows.
  3. Limitations in throughput
    Traditional workflows lack the capacity to handle the increasing sizes and intricacies of pathology datasets.
  4. Manual intervention
    Time-consuming manual data manipulation amplifies the risk for errors and prolongs the path to insights.

Experience next-generation “samples to insights”

Unrivaled AI-powered spatial image analysis

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Rapidly process hundreds of images in parallel

Cloud-based design optimizes performance and increases throughput by 5-100x

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Effortless high-confidence insights

Deep learning models seamlessly adapt to biomarker, artifact, and tissue variability, delivering robust AI-powered cell classification

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Easily customize your spatial analysis

Focus on sub-populations of interest by quickly defining custom phenotypes and regions

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Collaborative portal

Easy-to-use web portal allows flexible access to data for downstream analysis

Unprecedented spatial insights

Unprecedented spatial insights

Determine tissue segmentation, cellular spatial relationships, biomarker localization within the tissue, and more.


Meet STARVUE™

Our automated STARVUE™ (Spatial Tissue Analytics & Reporting for VUE panels) platform combines the latest innovations in artificial intelligence (AI) and image data science to seamlessly analyze images from 8- or 12-plex InSituPlex® assays at scale to generate high-confidence spatial insights into the intra- and inter-cellular dynamics of the tissue microenvironment.

Start your path to deeper spatial insights

Discover the STARVUE™ platform, a comprehensive end-to-end solution

Tissue Slides]

mIF and H&E

powered by InSituPlex®

Upload your samples stained with our InSituPlex® technology OR Submit your samples and our experts will stain for you with optional same-section H&E.

InSituPlex® assays use a proprietary isometric, single-molecule signal amplification chemistry that directly correlates detected signal intensity to the number of target biomarkers.

Image quality reviewed by our experts

Three Tissue Slides]

Image co-registration

with UltiStacker.AI™

We configure and run image co-registration.

UltiStacker.AI™ performs high throughput image co-registration of whole slide InSituPlex® 8- or 12-plex biomarker assay images.

]

Image analysis

with UltiAnalyzer.AI™

AI-driven image analysis with flexible phenotyping

UltiAnalyzer.AI™ utilizes deep-learning models to analyze biomarkers within composite whole slide mIF images at scale. Cell-level quantitative data is generated based on cell morphology and detected signal intensities.

Analyzed slides reviewed with Omero Plus

Omero Plus

Image Analysis Results]

Image analysis results

Deep characterizations are reported in portal

Direct links to third-party data management and analytics platforms enable deep characterization.


Integrated, Full Lifecycle Spatial Analysis

Gain powerful insights through an integrated ecosystem that streamlines your entire workflow from image management to in-depth analysis, all within a unified platform. STARVUE™ leverages AWS cloud infrastructure to power your spatial biology analysis. Concentriq allows you to document, manage, and visualize your whole slide stained images. Once analyzed, seamlessly transition to Omero Plus to explore the AI-identified cells, markers, and phenotypes within your slides.

Concentriq UI

Concentriq

Omero Plus


Comprehensive Data Package

  • Slide-level statistics optimized for seamless manual examination
  • Machine-readable data tables compatible with downstream data analysis tools
  • Cell-level data provided for further exploration
  • Spatial phenomics report for advanced spatial or cohort-level analysis (available add-on)
Data Package Chart

Ready to Get Started?

Partner with us for services or join our early access program

STARVUE™ Image Analysis Services

Looking for image analysis services or help choosing the right biomarkers to visualize your data?

We are committed to helping you create robust solutions that illuminate the value of your data.

Standard image analysis

Standard image analysis can be applied to any pre-configured or custom panel of biomarkers. Improve your understanding of the biological processes at work in your tissues with a quantitative summary of the regions and phenotypes present.

  • Identify cell populations in the tissue
  • Classify meaningful phenotypes based on the biomarkers
  • Define specific tumor and non-tumor regions
  • Look at the specific phenotypes within those compartments

Custom image analysis

Customized image analysis allows you to get a more in-depth and tailored analysis of the tissues. With expertise in both the latest scientific findings and deep technical knowledge of image and data analysis, we will work together with you to create robust and meaningful solutions.

  • Evaluate spatial relationships
  • Look at cell clustering, dispersion, and co-localization
  • Find immune excluded regions and much more
  • Compare biomarker profiles
  • Confirm differences between groups within the data set
  • Look at the effects of different treatment plans over time
Contact Us About Services

STARVUE™ SaaS Early Access Program

Already using InSituPlex® assays in your laboratory?

Learn how you can upload your images into STARVUE™ as part of our early access program.

Contact Us About STARVUE™ Early Access

Powerful image analysis starts with UltiStacker.AI and UltiAnalyzer.AI

UltiStacker.AI

Unmatched accuracy and efficiency through streamlined batch stacking of entire slide cohorts with high-throughput parallel processing.

  • Fast, robust image co-registration
  • Processes up to 300 slides/hour
  • Utilizes AI for higher quality and less manual effort
  • Improves H&E co-registration using AI-generated synthetic DAPI from H&E
See Our UltiStacker.AI Poster

UltiAnalyzer.AI

Superior sensitivity and robustness with state-of-the-art deep learning-enabled mIF analysis.

  • Leverages AI to enable mIF analysis at scale
  • Deep learning-enabled analysis for
    • Tissue detection
    • Region segmentation
    • Nuclei segmentation
    • Positive cell detection
See Our UltiAnalyzer.AI Poster

Expert Spotlight

Relevant for: Biopharma, CROs

For which indications is my drug candidate most efficacious?

After discovering an interesting drug candidate, finding the most promising indications to focus on for the next stage of drug development is often the next step. Once a predictive biomarker signature has been identified, this panel of markers can be applied across many indications.

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Relevant for: Biopharma, CROs

How does the tumor micro-environment change after treatment with a new drug?

After the identification and initial work to determine a potential new drug candidate, data from a small Phase 1 study with a low number of patients and multiple drug doses is available. Tumor samples were collected pre-treatment and post-treatment and from earlier studies the drug candidate’s expected mode of action is known.

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Relevant for: Biopharma, CROs

What is the most relevant assay for my study?

In the early exploratory phase of drug development, researchers need to identify the markers, phenotypes, spatial interactions which can best distinguish different patient groups, such as responders versus non-responders. There may be many ideas about which markers, phenotypes or spatial interactions might be predictive, but its important to narrow down this long list of possibilities to the most promising subset of markers.

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Ready to start generating powerful insights from your data?

Ready to start generating powerful insights from your data?