U-VUE Biomarker Datasheet - CD11b
|Alternative Name:||Integrin alpha-M|
|Main cell types:||Myeloid-derived cells – monocytes, macrophages, NK cells, granulocytes, myeloid dendritic cells|
|Subcellular Location:||Plasma membrane, intracellular, selective cytoplasmic expression in subset of immune cells|
|Positive control:||Tonsil, Spleen|
CD11b is an integrin alpha M chain protein and is expressed by myloid derived cells. It plays important role in adherance of leukocytes to stimulated endothelium and mediates uptake of the complement-coated particles.
IHC: Anti-CD11b antibody [SP331] staining normal tonsil FFPE tissue (brown). Hematoxylin counterstain in blue.
IHC: Anti-CD11b antibody conjugate [SP331] staining normal tonsil FFPE tissue (brown). Hematoxylin counterstain in blue.
ISP: Anti-CD11b antibody conjugate [SP331] staining normal tonsil FFPE tissue (green). Nuclear counterstain in blue.
Each lot of antibody conjugate reagent is quality control tested on positive control tissue and reviewed by Ultivue’s Pathology and Biomarker Analytics group to ensure appropriate staining patterns and signal intensity.
This U-VUE Antibody Conjugate is for Research Use Only. Not for Diagnostic purposes.