Panel Configurator

What type of panel do you want?

Select FlexVUE to quickly get started with 8 plex exchangeable panels or go to U-VUE for fully customized 2 to 8 plex panels.

Create your U-VUE™ panel

Guide: To create your panel, select from 2 to 8 markers from the U-VUE menu. Choose the cellular and functional categories to see the available markers or search directly for the markers you need. Simply drag and drop the markers onto the custom panel configurator on the right. Descriptions of all markers are located below the two boxes. When you are satisfied with your panel, give it a name and click on Request Panel (minimum delivery size of 3 kits).

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Categories
Results
All markers
Checkpoints
Exhaustion
TAMs
Myeloid
Functional
Dendritic
Stromal
TLS
Cell Signaling
T cell Regulation
TILS
B cells
Alpha-SMA
Alpha-SMA
ARG1
ARG1
BCL-2
BCL-2
BCL-XL
BCL-XL
BCMA
BCMA
Beta-Catenin
Beta-Catenin
BIM
BIM
CD11b
CD11b
CD11c
CD11c
CD138
CD138
CD14
CD14
CD15
CD15
CD155
CD155
CD16
CD16
CD163
CD163
CD19
CD19
CD20
CD20
CD206
CD206
CD22
CD22
CD27
CD27
CD28
CD28
CD299
CD299
CD3
CD3
CD31
CD31
CD335
CD335
CD38
CD38
CD39
CD39
CD4
CD4
CD40
CD40
CD45RO
CD45RO
CD56
CD56
CD68
CD68
CD70
CD70
CD73
CD73
CD8
CD8
CD80
CD80
CD86
CD86
CD96
CD96
CK
CK
CLEC10a
CLEC10a
CLEC9a
CLEC9a
CTLA4
CTLA4
Desmin
Desmin
FoxP3
FoxP3
GrzB
GrzB
HLA-DR
HLA-DR
IDO1
IDO1
iNOS
iNOS
Ki67
Ki67
LAG3
LAG3
MCL-1
MCL-1
MHC II
MHC II
PAX5
PAX5
PD-1
PD-1
PD-L1
PD-L1
SOX10
SOX10
TCF1/TCF7
TCF1/TCF7
TIGIT
TIGIT
My custom panel

Choose the number of markers starting at 2 up to 8 and select from the list from the left and drag and drop them.

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Price: Please log in/register here to get the prices displayed

Create your U-VUE™ panel

Guide: To create your panel, select from 2 to 8 markers from the U-VUE menu. Choose the cellular and functional categories to see the available markers or search directly for the markers you need. Simply drag and drop the markers onto the custom panel configurator on the right. Descriptions of all markers are located below the two boxes. When you are satisfied with your panel, give it a name and click on Request Panel.

Pre-optimized markers

Marker descriptions
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Results

Alpha-SMA
ARG1
BCL-2
BCL-XL
BCMA
Beta-Catenin
BIM
CD11b
CD11c
CD138
CD14
CD15
CD155
CD16
CD163
CD19
CD20
CD206
CD22
CD27
CD28
CD299
CD3
CD31
CD335
CD38
CD39
CD4
CD40
CD45RO
CD56
CD68
CD70
CD73
CD8
CD80
CD86
CD96
CK
CLEC10a
CLEC9a
CTLA4
Desmin
FoxP3
GrzB
HLA-DR
IDO1
iNOS
Ki67
LAG3
MCL-1
MHC II
PAX5
PD-1
PD-L1
SOX10
TCF1/TCF7
TIGIT

No markers have been exchanged yet

Price: Please log in/register here to get the prices displayed

Pre-defined FixVUE panels

Choose the pre-configured panel that best suits your research needs. Designed to assess the significant cell markers in the tissue microenvironment, these robust 4 and 8 plex panels are ready to use across multiple indications.

Prices are available from your local representative. Submit your configuration to learn more.

Immuno8 FixVUE Panel

Characterize T-cell subsets, immunosuppressive cells and interactions along the PD-L1/PD-1 checkpoint axis with this comprehensive immuno-oncology focused panel.

More details

Please log in/register here to get the prices displayed

PD-L1 FixVUE Panel

Determine whether the tumor is “hot” or “cold”. Co-localize macrophages, cytotoxic T cells, tumor cells, and the underlying inhibitory or inflammatory mechanisms at play along the PD-L1 axis.

More details

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T-reg FixVUE Panel

Identify regulatory T cells and cytotoxic T cells within the tumor context. Characterize the different T cells that regulate immune response.

More details

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MDSC FixVUE Panel

Identify Myeloid Derived Suppressor Cells within the tumor microenvironment. Characterize cell populations into M-MDSCs and PMN-MDSCs.

More details

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PD-1 FixVUE panel

Determine whether the immune response has exhausted. Co-localize T cells, memory T cells, tumor cells, and the underlying PD-1 checkpoint immune exhaustion mechanism at play.

More details

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T-act FixVUE Panel

Determine whether T cells have the potential to mediate cell death. Examine the co-expression of proliferating cells, cytotoxic cells, tumor cells, and the underlying proliferative index and potential for T cell mediated death.

More details

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APC FixVUE Panel

Identify and characterize professional antigen-presenting cells (APCs). Examine the co-expression and visualization of specific subsets of cells along the dendritic, monocyte/macrophage, and B cell lineages.

More details

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Not sure which panel you need?

Not sure which panel you need?

Talk to an expert

FAQs

What equipment do I need to run a FixVUE or FlexVUE panel in my lab?

All FixVUE and FlexVUE kits are delivered as a complete set of reagents to perform multiplex staining on up to 10 tissue slides per kit. In addition to the typical lab equipment needed to process tissue slides, InSituPlex assays have been optimized for use with the Leica Biosystems BOND RX automated stainer, or via a manual protocol when this autostainer is not available.

In addition, the use of UltiStacker software is recommended to perform same slide image fusion of both multiplex immunofluorescent (mIF) images and Hu0026amp;E images. Once co-registered with this software, the images are ready for use with image analysis software. UltiStacker is available upon request with any FixVUE or FlexVUE order.

For the complete list of requirements, please u003ca href=u0022/contactu0022u003econtact usu003c/au003e and we would be happy to set up a consultation with you.

Do I need to optimize the protocol for my tissue samples?

Multiplex assays using InSituPlex technology have been pre-optimized for use across indications, allowing you to eliminate time consuming optimization steps. The FixVUE and FlexVUE kits are ready to use out of the box, simply follow the included protocol to achieve unprecedented resolution across your entire tissue sample.

Find out more about u003ca href=u0022/panels/#insituplexu0022u003eInSituPlexu003c/au003e technology u003ca href=u0022/panels/#insituplexu0022u003ehere.u003c/au003e

The marker I need isn’t listed in the FlexVUE menu; how can I add it?

In addition to FlexVUE and FixVUE marker panels, we offer an extensive list of pre-optimized markers in our U-VUE menu. This fully customizable biomarker menu allows you to build the unique panel to fit your research needs. In addition, our experts are on hand to help you design, build and execute your assays either directly in your lab or through our CLIA certified services lab.

Find out more about U-VUE markers u003ca href=u0022/u-vueu0022u003ehereu003c/au003e or u003ca href=u0022/contactu0022u003econtact usu003c/au003e to help you get started building your custom panels.

Do you ship to my country?

Currently, ordering through our webshop is only available for organizations in the following countries: Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Luxembourg, Netherlands, Norway, Poland, Portugal, Slovakia, Spain, Sweden, Switzerland, Turkey, United Kingdom, and the United States.

If you are not located in these countries, please contact us u003ca href=u0022https://ultivue.com/sales/u0022u003ehereu003c/au003e to find out what shipping options may be available to you through our network of distributors.