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Contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types.
Development of specific pre-clinical mouse-specific multiplexed immunofluorescence (mIF) assays
Spatial multi-omics analysis
High throughput tissue phenotyping and imaging of tumor immune microenvironment
InSituPlex and Imaging Mass Cytometry
Novel workflow for ROI detection in high plex assays using InSituPlex
Optimized mIF using UltiMapper reagents with the ZEISS Axioscan 7 scanner
A multiplex assay to assess CD8 activation and tumor co-localization in FFPE tissues
Multiplex digital phenotyping across multiple tumor types
Gene expression profiling, digital spatial profiling and multiplex IF in HNSCC tumors
InSituPlex technology for deep phenotypic profiling of the TME
High-multiplex staining with InSituPlex technology
Novel 8-plex immunofluorescence within the TME
Sequential same slide IF and H&E for phenotypic and morphologic analysis
InSituPlex technology to support discovery of immune cell signatures in the TME
Comparing CD8 and PD-L1 expression in NSCLC using IF and a brightfield test
The value of same-slide multiplex IF and H&E staining
Multiplex IF for monitoring T-cell exhaustion in IBD and colorectal cancer
InSituPlex technology and tissue phenomics to monitor tumor immunity
InSituPlex multiplex immunofluorescence for Crohn’s Disease and Ulcerative Colitis
Comprehensive I/O profiling in NSCLC
Characterizing spatial distribution of immune-cell subsets in Nonalcoholic Steatohepatitis and Primary Sclerosing Cholangitis using a novel 12-plex Ultimapper ® kit
Phase 1 clinical trial for melanoma patients