Multiplex IHC Reagent Kits

Exceptional quality reagents for high performance marker multiplexing detection and analysis.

UltiMapper kits are specifically designed for the fast and comprehensive exploration of biologically-relevant markers in tissue samples for research applications. These fully-optimized, off the shelf multiplex IHC panels are able to provide same-day staining to results. With true co-localization of multiple markers, UltiMapper kits are able to support a deep level of single cell phenotyping from a limited set of markers.

Multiplex IHC Reagent Kits

Exceptional quality reagents for high performance marker multiplexing detection and analysis. UltiMapper™ kits are specifically designed for the fast and comprehensive exploration of biologically-relevant markers in tissue samples for research applications. These fully-optimized, off the shelf multiplex IHC panels are able to provide same day staining to results. With true co-localization of multiple markers, UltiMapper kits are able to support a deep level of single cell phenotyping from a limited set of markers.

Tumor tissue staining using the ultimapper I/O PDL-1 multiplex kit.

UltiMapper I/O PD-L1

Determine whether the tumor is “hot” or “cold”

Markers: CD8, CD68, PD-L1, panCK/SOX10

Phenotypes:

  • Cytotoxic immune cells
  • Immunosuppressive macrophages
  • Immune evading tumor cells
Spleen section staining using the ultimapper I/O T-reg multiplex IHC reagent kit.

UltiMapper I/O T-reg

Characterize regulatory T cells and cytotoxic T cells

Markers: CD8, CD4, FoxP3, panCK/SOX10

Phenotypes:

  • T helper cells
  • Regulatory T cells
  • Cytotoxic T cells
Tissue staining using the ultimapper I/O MDSC multiplex kit.

UltiMapper I/O MDSC

Profile myeloid-derived suppressor cells

Markers: CD11b, CD14, CD15, HLA-DR

Phenotypes:

  • Antigen-presenting cells
  • M-MDSCs
  • PMN-MDSCs
Tissue staining using the ultimapper I/O MDSC multiplex kit.

UltiMapper I/O PD-1

Determine whether the immune response has exhausted

Markers: CD3, CD45RO, PD-1, panCK/SOX10

Phenotypes:

  • Exhausted memory cells
  • Exhausted T cells
  • Exhausted memory T cells

UltiMapper I/O T-act

Determine whether T cells have the potential to mediate cell death

Markers: CD3, Granzyme B, Ki67, panCK/SOX10

Phenotypes:

  • Proliferating T cells
  • Cytotoxic T cells
  • Proliferating tumor cells
Spleen section staining using the ultimapper I/O T-reg multiplex IHC reagent kit.

UltiMapper I/O APC

Identify and characterize professional antigen-presenting cells (APCs)

Markers: CD11c, CD20, CD68/CD163, MHC II

Phenotypes:

  • Dendritic cells
  • B cells
  • Macrophages

For Research Use Only, not for use in diagnostic procedures

Explore our Technology

Our proprietary InSituPlex technology enables unsurpassed biomarker detection and analysis in tissue, with no compromise on level of multiplexing, throughput of sample staining and imaging, and without requiring dedicated instrumentation.

Explore our Services

Services and Biomarker Programs

With speed and flexibility at heart, our Staining & Imaging services and Biomarker Programs offer highly customizable panels to include all your markers of interest.

product

Explore our Technology

InSituPlex®

Our proprietary InSituPlex technology enables unsurpassed biomarker detection and analysis in tissue, with no compromise on level of multiplexing, throughput of sample staining and imaging, and without requiring dedicated instrumentation.

Services

Explore our Services

Standard and Custom Services

With speed and flexibility at heart, our Biomarker Programs offer validated 5-Plex in addition to highly customizable panels to include all your markers of interest

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