Presented at: AACR 2021
Comparative multiplex digital phenotyping of the tumor microenvironment across multiple tumor types using a well characterized multi-tumor tissue microarray
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Collaboration, FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Christopher Womack, Milan Bhagat, Angela Vasaturo, Mael Manesse and Lorcan Sherry (TriStar, OracleBio)