Presented at: AACR 2021
Relevant for
Collaboration, FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Christopher Womack, Milan Bhagat, Angela Vasaturo, Mael Manesse and Lorcan Sherry (TriStar, OracleBio)
Relevant for
FixVUE, FlexVUE, InSituPlex, U-VUE
Description Given the rapid progress in the field of immuno-oncology and techniques such as single-cell phenotyping theres a need to create an urgency around multiplex investigations with single-cell resolution that retain tissue context.
Associate Director Scientific Affairs, Ultivue; Dept of Medical Oncology, University Hospital Brussels
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Angela Vasaturo is the Associate Director Scientific Affairs at Ultivue. Prior to joining Ultivue she was a Senior Researcher in Dr. Jerome Galon’s Laboratory of Integrative Cancer Immunology at the Cordeliers Research Centre. She has a wealth of expertise in multiplex IHC techniques, multispectral digital pathology, and tissue imaging.
Associate Director, Scientific Affairs Ultivue ;Tissue Hybridization Scientific Lead, Queens University Belfast
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Angela Vasaturo is the Associate Director Scientific Affairs at Ultivue. Prior to joining Ultivue she was a Senior Researcher in Dr. Jerome Galon’s Laboratory of Integrative Cancer Immunology at the Cordeliers Research Centre. She has a wealth of expertise in multiplex IHC techniques, multispectral digital pathology, and tissue imaging.
At Queens University Belfast, Matt is the Scientific Lead for Tissue Hybridization and Digital Pathology in the Precision Medicine Centre of Excellence. Matt is responsible for the TH&DP team. Their remit was to deliver academic research studies, clinical trials, and industry projects within the PMC.
Presented at: AACR 2021
Relevant for
Collaboration, FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Presented at: AACR 2021
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Presented at: AACR 2021
Relevant for
Collaboration, FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Presented at: AACR 2021
Relevant for
Collaboration, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Relevant for
Collaboration, FixVUE, InSituPlex
Description Given the rapid progress in the field of immuno-oncology and techniques such as single-cell phenotyping theres a need to create an urgency around multiplex investigations with single-cell resolution that retain tissue context.
Anne Hellebust, Kyla Teplitz, Katir K Patel, Karan Sharma, Amanda Bares, Mael Manesse, Mark Burton, Bonnie Phillips, Sean Downing and Kate Lillard
Relevant for
Collaboration, FixVUE, InSituPlex
Description Overview highlighting InSituPlex technology coupled to the SLIDEVIEW VS200 scanner to produce high-quality, aligned images of eight targets in FFPE tumor sections
Amanda Bares, Alec De Grand, Douglas Wood and Maël Manesse
Presented at: AACR 2021
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Christopher Womack, Milan Bhagat, Angela Vasaturo, Mael Manesse and Lorcan Sherry (TriStar, OracleBio)
Presented at: AACR 2021
Relevant for
Collaboration, FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Presented at: AACR 2021
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Presented at: AACR 2021
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Presented at: AACR 2021
Relevant for
FixVUE, InSituPlex
Description The tumor microenvironment (TME) represents a complex interaction of immune and host cellsand can be described broadly as ‘inflamed’, ‘immune excluded’ and ‘desert’; categories that mayserve as predictive parameters for response to different immunotherapies. Multiplexedfluorescence and associated digital imaging platforms are important tools for defining the spatialcomponents of the TME and can accelerate development of novel immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Christopher Womack, Milan Bhagat, Angela Vasaturo, Mael Manesse and Lorcan Sherry (TriStar, OracleBio)
Image analysis
5824
Comparative multiplex digital phenotyping of the tumor microenvironment across multiple tumor types using a well characterized multi-tumor tissue microarray
