Improving the diagnostic accuracy of the PD-L1 test with multiplexing and image analysis

Description Targeting of the programmed cell death protein (PD-1)/programmed death-ligand 1 (PD-L1) axis with checkpoint inhibitors has changed clinical practice in non-small cell lung cancer (NSCLC). However, clinical assessment remains complex and ambiguous. During this webinar, Matt Humphries from the Patrick G Johnson Centre for Cancer Research at Queens University, Belfast will discuss results presented in a recently published paper in the journal Cancers, “Improving the Diagnostic Accuracy of the PD-L1 Test with Image Analysis and Multiplex Hybridization.” In this study, the authors assessed whether the application of digital image analysis (DIA) and multiplex immunofluorescence to digital PD-L1 immunohistochemistry (IHC) slides has the potential to improve the accuracy and reproducibility of PD-L1 diagnostic tests.