Spatial biology
5880 Getting TiME on Your Side: Defining the future of precision medicine with advanced multiplexed immunofluorescence
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Getting TiME on Your Side: Defining the future of precision medicine with advanced multiplexed immunofluorescence

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Relevant for

FixVUE, InSituPlex, U-VUE

Description Overview highlighting the use of the InSituPlex® (ISP) a novel, robust mIF assay technology reliant on conjugating DNA barcodes to antibodies and using sequence-specific DNA-DNA hybridization tolabel antibodies for spatial profiling of immuno-oncology targets in FFPE tumor tissue

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5801 Multidimensional Multiplexing for Spatially Resolved Immune Tumor Heterogeneity
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webinar
Ralf Huss MD, PhD

Senior Field Applications Scientist, Ultivue

Multidimensional Multiplexing for Spatially Resolved Immune Tumor Heterogeneity

Length: 55 minutes

Relevant for

FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Meet the host

Ralf Huss is a Professor of Pathology and the managing deputy director of Pathology and Molecular Diagnostics at the University Hospital in Augsburg (Germany), where he also leads the Center for Digital Medicine. He is board-certified in anatomical, experimental, and molecular pathology with more than 30 years of experience in histopathology, immunology, cancer research and oncology.

Author
Ralf Huss MD, PhD

Senior Field Applications Scientist, Ultivue

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5740 Advanced Phenotyping of the Tumor Immune Microenvironment
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webinar
Angela Vasaturo, PhD; Fabian Schneider, PhD

Associate Director, Scientific Affairs; Senior Scientist, Visiopharm

Advanced Phenotyping of the Tumor Immune Microenvironment

Length: 55 minutes

Relevant for

Collaboration, FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Meet the host

Ralf Huss is a Professor of Pathology and the managing deputy director of Pathology and Molecular Diagnostics at the University Hospital in Augsburg (Germany), where he also leads the Center for Digital Medicine. He is board-certified in anatomical, experimental, and molecular pathology with more than 30 years of experience in histopathology, immunology, cancer research and oncology.

Author
Ralf Huss MD, PhD

Senior Field Applications Scientist, Ultivue

Dr. Fabian Schneider is part of Visiopharm’s R&D and Product Management team, responsible for phenotyping products as well as service projects for custom APP development. Fabian has over 10 years of international experience in cancer biology and immuno-oncology, working in academic research labs, clinical research teams and computational pathology groups in both academia and biopharma. Fabian received his Dr phil. nat. in Cell Biology in 2011 from the Johan Wolfgang Goethe University Frankfurt, Germany.

Author
Fabian Schneider, PhD

Senior Scientist, Visiopharm

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 6017 Fast and accurate spatial phenotyping and immuno-profiling using Ultivue UltiMapper kits and the ZEISS Axioscan 7 slide scanner
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Fast and accurate spatial phenotyping and immuno-profiling using Ultivue UltiMapper kits and the ZEISS Axioscan 7 slide scanner

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Relevant for

Collaboration, FixVUE, InSituPlex

Description We describe the potential of accurate cellular phenotyping using the InSituPlex technology with fast whole-slide scanning using ZEISS Axioscan 7, an automated slide scanning system for fluorescence and transmitted light applications with modern cameras, a sophisticated focusing method and a powerful imaging software. The compounded effect of integrating these technologies can significantly improve the throughput of immuno-oncology research.

Authors

Catherine Benson, Keith Wharton, Gourab Chatterjee, Markus Neumann, Volker Döring and Maël Manesse

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5824 Comparative multiplex digital phenotyping of the tumor microenvironment across multiple tumor types using a well characterized multi-tumor tissue microarray
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poster

Presented at: AACR 2021

Comparative multiplex digital phenotyping of the tumor microenvironment across multiple tumor types using a well characterized multi-tumor tissue microarray

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Relevant for

Collaboration, FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Authors

Marie Cumberbatch, Douglas Wood, Christopher Womack, Milan Bhagat, Angela Vasaturo, Mael Manesse and Lorcan Sherry (TriStar, OracleBio)

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5876 Riding the Next Wave of Diagnostic Test Development with InSituPlex
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ebook

Riding the Next Wave of Diagnostic Test Development with InSituPlex

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Relevant for

FixVUE, FlexVUE, InSituPlex, U-VUE

Description Overview highlighting the use of the InSituPlex® (ISP) a novel, robust mIF assay technology reliant on conjugating DNA barcodes to antibodies and using sequence-specific DNA-DNA hybridization tolabel antibodies for spatial profiling of immuno-oncology targets in FFPE tumor tissue

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5791 Improving the diagnostic accuracy of the PD-L1 test with multiplexing and image analysis
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webinar
Angela Vasaturo, PhD; Matt Humphries, PhD

Associate Director, Scientific Affairs Ultivue ;Tissue Hybridization Scientific Lead, Queens University Belfast

Improving the diagnostic accuracy of the PD-L1 test with multiplexing and image analysis

Length: 55 minutes

Relevant for

FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Meet the host

Ralf Huss is a Professor of Pathology and the managing deputy director of Pathology and Molecular Diagnostics at the University Hospital in Augsburg (Germany), where he also leads the Center for Digital Medicine. He is board-certified in anatomical, experimental, and molecular pathology with more than 30 years of experience in histopathology, immunology, cancer research and oncology.

Author
Ralf Huss MD, PhD

Senior Field Applications Scientist, Ultivue

At Queens University Belfast, Matt is the Scientific Lead for Tissue Hybridization and Digital Pathology in the Precision Medicine Centre of Excellence. Matt is responsible for the TH&DP team. Their remit was to deliver academic research studies, clinical trials, and industry projects within the PMC.

Author
Matt Humphries, PhD

Tissue Hybridization Scientific Lead, Queens University Belfast

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5867 High-multiplex automated staining and scanning workflow with Ultivue InSituPlex technology and the Olympus SLIDEVIEW VS200 slide scanner
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poster

Presented at: AACR 2020

High-multiplex automated staining and scanning workflow with Ultivue InSituPlex technology and the Olympus SLIDEVIEW VS200 slide scanner

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Relevant for

Collaboration, FixVUE, InSituPlex

Authors

Amanda Bares, Alec De Grand, Douglas Wood and Maël Manesse

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5865 Gene Expression Profiling, Digital Spatial Profiling and Multiplex Immunohistochemistry of the Tumor-Immune Microenvironment in HNSCC Tumors
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poster

Presented at: AACR 2021

Gene Expression Profiling, Digital Spatial Profiling and Multiplex Immunohistochemistry of the Tumor-Immune Microenvironment in HNSCC Tumors

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Relevant for

Collaboration, FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5861 Introduction of a robust workflow for the whole whole-side acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay
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poster

Presented at: AACR 2021

Introduction of a robust workflow for the whole whole-side acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay

Register here for download

Relevant for

Collaboration, FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5859 Measuring concordance of CD8 and PD-L1 expression in Non-Small Cell Lung cancer between a novel multiplex immunofluorescence assay and a brightfield laboratory developed test
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poster

Presented at: AACR 2021

Measuring concordance of CD8 and PD-L1 expression in Non-Small Cell Lung cancer between a novel multiplex immunofluorescence assay and a brightfield laboratory developed test

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Relevant for

FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5855 Sequential same slide multiplex immunofluorescence and H&E staining for combined phenotypic and morphologic characterization of formalin-fixed paraffin-embedded tissue sections
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poster

Presented at: AACR 2021

Sequential same slide multiplex immunofluorescence and H&E staining for combined phenotypic and morphologic characterization of formalin-fixed paraffin-embedded tissue sections

Register here for download

Relevant for

Collaboration, FixVUE, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5846 Utilizing image analysis to characterize an 8-plex immunofluorescence immune checkpoint biomarker panel within the tumor tissue microenvironment
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poster

Presented at: AACR 2021

Utilizing image analysis to characterize an 8-plex immunofluorescence immune checkpoint biomarker panel within the tumor tissue microenvironment

Register here for download

Relevant for

Collaboration, InSituPlex

Description During this webinar, Dr. Ralf Huss from University Hospital in Augsburg discussed how understanding the entire tumor heterogeneity, its immune environment, and contextual relationship requires the spatial quantification of different immune and tumor cells along with the genetic background of the individual cancer.

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5874 Introduction of a robust workflow for the whole-slide acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay
shape book
ebook

Introduction of a robust workflow for the whole-slide acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay

Register here for download

Relevant for

Collaboration, FixVUE, InSituPlex

Description Overview highlighting the use of the InSituPlex® (ISP) a novel, robust mIF assay technology reliant on conjugating DNA barcodes to antibodies and using sequence-specific DNA-DNA hybridization tolabel antibodies for spatial profiling of immuno-oncology targets in FFPE tumor tissue

Authors

Anne Hellebust, Kyla Teplitz, Katir K Patel, Karan Sharma, Amanda Bares, Mael Manesse, Mark Burton, Bonnie Phillips, Sean Downing and Kate Lillard

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5871 High-multiplex automated staining and scanning workflow with Ultivue InSituPlex technology and the Olympus SLIDEVIEW VS200 slide scanner
shape book
ebook

High-multiplex automated staining and scanning workflow with Ultivue InSituPlex technology and the Olympus SLIDEVIEW VS200 slide scanner

Register here for download

Relevant for

Collaboration, FixVUE, InSituPlex

Description Overview highlighting InSituPlex technology coupled to the SLIDEVIEW VS200 scanner to produce high-quality, aligned images of eight targets in FFPE tumor sections

Authors

Amanda Bares, Alec De Grand, Douglas Wood and Maël Manesse

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

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