RNA scope
5848 Spatial multi-omics analysis targeting protein and RNA biomarkers on a single FFPE tissue section using an integrated staining and imaging workflow
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poster

Presented at: AACR 2022

Spatial multi-omics analysis targeting protein and RNA biomarkers on a single FFPE tissue section using an integrated staining and imaging workflow

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Relevant for

FixVUE, InSituPlex, RNA scope

Description Our poster outlines the protocol to demonstrate the compatibility of Ultivue InSituPlex® (ISP) assays for protein detection with a commercially available RNAScope® assay (Advanced Cell Diagnostics, Inc.) for RNA detection. This protocol and data shown highlights the value of an integrated ISP-in situ hybridization (ISH) workflow for co-detection of protein and RNA targets on a single FFPE tissue section, showcasing the value of both phenotypic and transcriptomic analyses in the field of spatial biology.

Authors

Gourab Chatterjee, Grace Vezeau, Milena Lazova, Michael Sismour and Mael Manesse

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