Director of Scientific Affairs, Ultivue
Relevant for
InSituPlex, OmniVUE™, Spatial Image Analysis, U-VUE
Description The determination of robust biomarkers is crucial for the successful development and deployment of precision cancer therapies. This presentation highlights a novel approach to accelerate biomarker discovery and spatial biology research by combining ultra-sensitive multiplex assays with AI-powered image analysis. This powerful combination allows researchers to gain deeper insights into the complexities of the tumor microenvironment. Overview of what is addressed: The use of a unique DNA-barcoded antibody technology and its impact on enabling highly sensitive and robust multiplex biomarker detection. How this approach allows for the flexible design of customized panels to suit specific research questions. Data demonstrating the technology’s high degree of reproducibility and accuracy in quantifying biomarker expression, even for low abundance targets.
Dr. Angela Vasaturo is Director of Scientific Affairs at Ultivue. Prior to Ultivue, Angela was a Senior Researcher in Dr. Jerome Galon’s Laboratory of Integrative Cancer Immunology at the Cordeliers Research Center. Angela was among the first in Europe to be involved in the development of multiplex IHC and multispectral imaging and analysis of up to six immunofluorescence markers, and today is considered a leading European expert in multiplex IHC techniques, digital pathology, spatial biology, and tissue imaging.
Presented at: AACR 2024
Relevant for
InSituPlex, OmniVUE™, U-VUE
Description Our poster presents a simple, rapid, and robust workflow for performing Ultivue InSituPlex® mIF assays with OmniVUE™ panels on the Parhelia Omni-Stainer™. Tight slide temperature control and lower volume reagent used by the Omni-Stainer™ supports consistent, high performance, high throughput whole slide multiplexed biomarker detection for translational and clinical studies.
Kevin Hwang, Laura Duro, Alex Veith, Nelson Wedin, Nikolay Samisik, Je H. Lee.
Principal Software Engineer
Relevant for
FixVUE, FlexVUE, InSituPlex, U-VUE
Description Douglas Wood, Principal Software Engineer, introduced our image stacking tool to help you achieve perfectly co-registered images, ready for image analysis. Whether you want to co-register images from our 8-plex panels or want to compare same-slide H&E with IF images, UltiStacker is an essential tool to achieve beautiful results.
Doug is the designer and developer of UltiStacker™.
He has extensive experience developing applications for scientific image processing, visualization, and analysis.
Relevant for
FixVUE, InSituPlex, U-VUE
Description Overview highlighting the use of the InSituPlex® (ISP) a novel, robust mIF assay technology reliant on conjugating DNA barcodes to antibodies and using sequence-specific DNA-DNA hybridization tolabel antibodies for spatial profiling of immuno-oncology targets in FFPE tumor tissue
Relevant for
FixVUE, FlexVUE, InSituPlex, U-VUE
Description Overview highlighting the use of the InSituPlex® (ISP) a novel, robust mIF assay technology reliant on conjugating DNA barcodes to antibodies and using sequence-specific DNA-DNA hybridization tolabel antibodies for spatial profiling of immuno-oncology targets in FFPE tumor tissue
