Spatial biology
5863 Looking beyond the assay: Comparison of multiplex chromogenic and fluorescent immuno-histochemistry for standardized immune oncology profiling in non-small cell lung carcinoma patients
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Presented at: SITC 2019

Looking beyond the assay: Comparison of multiplex chromogenic and fluorescent immuno-histochemistry for standardized immune oncology profiling in non-small cell lung carcinoma patients

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Authors

Ana Hidalgo Sastre, Lorenz Rognoni Monika Baehner, Marco Testori, Jessica Chan, Andreas Spitzmüller, Nicolas Brieu, Bonnie Phillips, Katir K. Patel, Sean R. Downing, Alex Haragan, John K. Field and Florian Leiss

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Categories: 5857 Tissue-based characterization of T cell exhaustion in inflammatory bowel disease and colorectal cancer using multiplex IHC
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Presented at: SITC 2019

Tissue-based characterization of T cell exhaustion in inflammatory bowel disease and colorectal cancer using multiplex IHC

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Ana Hidalgo Sastre, Lorenz Rognoni Monika Baehner, Marco Testori, Jessica Chan, Andreas Spitzmüller, Nicolas Brieu, Bonnie Phillips, Katir K. Patel, Sean R. Downing, Alex Haragan, John K. Field and Florian Leiss

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Categories: 5845 Tumour immunity signatures to expand current diagnostic approaches in mismatch repair deficient cancers in the context of Lynch syndrome through InSituPlex technology and Tissue Phenomics integration
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Presented at: SITC 2019

Tumour immunity signatures to expand current diagnostic approaches in mismatch repair deficient cancers in the context of Lynch syndrome through InSituPlex technology and Tissue Phenomics integration

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Authors

Ana Hidalgo Sastre, Lorenz Rognoni Monika Baehner, Marco Testori, Jessica Chan, Andreas Spitzmüller, Nicolas Brieu, Bonnie Phillips, Katir K. Patel, Sean R. Downing, Alex Haragan, John K. Field and Florian Leiss

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Categories: 5821 A phase I clinical trial on intratumoral administration of autologous CD1c (BDCA-1)+ myeloid dendritic cells (myDC) plus talimogene laherparepvec (T-VEC) in patients with advanced melanoma
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Presented at: SITC 2019

A phase I clinical trial on intratumoral administration of autologous CD1c (BDCA-1)+ myeloid dendritic cells (myDC) plus talimogene laherparepvec (T-VEC) in patients with advanced melanoma

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Authors

Ana Hidalgo Sastre, Lorenz Rognoni Monika Baehner, Marco Testori, Jessica Chan, Andreas Spitzmüller, Nicolas Brieu, Bonnie Phillips, Katir K. Patel, Sean R. Downing, Alex Haragan, John K. Field and Florian Leiss

Authors

Schwarze JK., Awada G., Cras L., Forsyth R., Dufait I., Van Reit I. and Neyns B.

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Categories: 5827 Use of Ultivue InSituPlex®Multiplex Immunofluorescence to Localize and Quantify Regulatory T Lymphocytes in Crohn’s Disease and Ulcerative Colitis
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Presented at: SITC 2019

Use of Ultivue InSituPlex®Multiplex Immunofluorescence to Localize and Quantify Regulatory T Lymphocytes in Crohn’s Disease and Ulcerative Colitis

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Authors

Ana Hidalgo Sastre, Lorenz Rognoni Monika Baehner, Marco Testori, Jessica Chan, Andreas Spitzmüller, Nicolas Brieu, Bonnie Phillips, Katir K. Patel, Sean R. Downing, Alex Haragan, John K. Field and Florian Leiss

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Categories: 5973 A multiplex immunofluorescence assay to assess immune checkpoint inhibitor targeted CD8 activation and tumor co-localization in FFPE tissues Copy
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Presented at: SITC 2019

A multiplex immunofluorescence assay to assess immune checkpoint inhibitor targeted CD8 activation and tumor co-localization in FFPE tissues Copy

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Authors

Ana Hidalgo Sastre, Lorenz Rognoni Monika Baehner, Marco Testori, Jessica Chan, Andreas Spitzmüller, Nicolas Brieu, Bonnie Phillips, Katir K. Patel, Sean R. Downing, Alex Haragan, John K. Field and Florian Leiss

Authors

Schwarze JK., Awada G., Cras L., Forsyth R., Dufait I., Van Reit I. and Neyns B.

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Categories: 5882 Case Study: A multiplex immunofluorescence assay to assess immune checkpoint inhibitor-targeted CD8 activation and tumor co-localization in FFPE tissues
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Case Study: A multiplex immunofluorescence assay to assess immune checkpoint inhibitor-targeted CD8 activation and tumor co-localization in FFPE tissues

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Description Developing a multiplex immunofluorescence assay for the in depth characterization of activatedT cells in tumor tissue samples.

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