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“As early investors in Ultivue, we remain impressed by the differentiation InSituPlex® and the company’s software technologies like Ultistacker® offer to the rapidly expanding field of spatial biology,” said Andrea Jackson, Partner at Northpond Ventures.

In addition to its financing, Ultivue also announced the hire of Rob Carson as President and Chief Executive Officer. Mr. Carson brings more than 20 years of life sciences industry experience, including in the areas of commercial leadership, strategy and transformation, R&D and operations. He previously held GM and other executive roles at Medtronic plc, Waters Corporation and Harbinger Health.

“We’re pleased to welcome Rob to the Ultivue board and as the company’s new CEO.  We’re committed to partnering with the Ultivue team as it executes its plan for customer success and continued company growth,” said Keith Crandell, co-founder and Managing Director at ARCH Venture Partners.

Mr. Carson added, “I’m excited to join Ultivue and particularly by the company’s core of passion and expertise. Leveraging InSituPlex® and our proprietary AI capabilities, we have the opportunity to speed the development process of novel therapeutics and to provide unrivaled signal-to-noise performance for our biopharma, CRO and academic partners studying proteins in their spatial context.”

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Combining Ultivue’s mIF assays with the Olympus SLIDEVIEW™ VS200 research slide scanner provides a convenient, fast tool for whole slide mIF imaging in translational studies for researchers in academia, biotech, pharma and contract research organizations in the Americas. The collaboration builds on their existing partnership to meet the scientific community’s increasing need for fluorescent multiplexing.

Ultivue develops unique solutions for mIF applications, imaging and spatial phenomics. Its proprietary InSituPlex® technology enabling improved signal-to-noise data is designed for fast and comprehensive exploration of up to 12 biologically relevant targets in one tissue slide, with same-slide hematoxylin and eosin (H) analysis in tissue samples. This technology combines the power of computational pathology and spatial biology to guide translational science in immuno-oncology.

Evident Corporation, a wholly owned subsidiary of Olympus Corporation, manufacturers leading-edge life science microscopes that support a broad range of academic and clinical research areas, pathology diagnostic services and the growing demand for novel drug discovery. The Olympus VS200 slide scanner has advanced the field of whole slide imaging with high-quality optics, fast scanning and flexible imaging options that include a robust solution for fluorescent multiplexing.

“We are excited to enhance our relationship with Evident to further optimize the integration of Ultivue assays on the SLIDEVIEW VS200 research slide scanner. We jointly enable highly efficient workflows to drive adoption of tissue multiplexing on larger cohorts,” said Florian Leiss, PhD, the Vice President of Product Strategy and Corporate Development at Ultivue.

“We are delighted to continue to collaborate with Ultivue to provide a total solution for multiplexing,” said Lee Wagstaff, the Vice President of Life Science Sales and Marketing at Evident Americas. “With Ultivue’s assays and our slide scanning technology, we can provide a complete workflow solution for our customers that enables them to work more efficiently.”

About EVIDENT

At Evident, we are guided by the scientific spirit—innovation and exploration are at the heart of what we do. Committed to making people’s lives healthier, safer and more fulfilling, we support our customers with solutions that solve their challenges and advance their work, whether it is researching medical breakthroughs, inspecting infrastructure, or exposing hidden toxins in consumer products.

Evident Life Science empowers scientists and researchers through collaboration and cutting-edge life science solutions. Dedicated to meeting the challenges and supporting the evolving needs of its customers, Evident Life Science advances a comprehensive range of microscopes for pathology, hematology, IVF, and other clinical applications as well as for research and education.

For more information, EvidentScientific.com.

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Ultivue VUE panels for multiplex immune-labeling offer endless options for researchers to characterize complex, tissue immune biology. With unprecedented signal-to-noise and options for pre-designed panels or customized panels, Ultivue solutions are designed to label tissues for in-depth data mining for spatial phenomics. The ZEISS Axioscan automated whole slide imager offers unparalleled fluorescence imaging and resolution of multiplex immuno-labeled samples. Fast and gentle imaging ensures high productivity with little to no sample damage. With this collaboration, Ultivue and ZEISS will offer researchers a faster time to results from tissue labeling to image acquisition through analysis.

“At Ultivue, we have successfully scanned thousands of tissue sections stained with our multiplex assays with the ZEISS Axioscan to serve our biopharma customers. High throughput, quality, and cost-efficiency are key characteristics of a scalable workflow for tissue multiplexing. We are excited to deepen our relationship with ZEISS to further optimize the interplay of Ultivue assays and ZEISS instruments,” said Jacques Corriveau President and CEO of Ultivue.

“Building on our six-year relationship, we are looking forward to a deeper level of collaboration with Ultivue to co-market our complete end-to-end workflow for spatial phenotyping from staining to imaging to analysis,” said Joseph Huff, Head of Marketing North America ZEISS Research Microscopy Solutions.

Figure 1. Tonsil stained with Ultivue’s FixVUE Immuno8 panel and scanned using a ZEISS Axioscan.

About ZEISS

ZEISS is an internationally leading technology enterprise operating in the fields of optics and optoelectronics. In the previous fiscal year, the ZEISS Group generated annual revenue totaling 7.5 billion euros in its four segments Semiconductor Manufacturing Technology, Industrial Quality & Research, Medical Technology and Consumer Markets (status: 30 September 2021).

For its customers, ZEISS develops, produces and distributes highly innovative solutions for industrial metrology and quality assurance, microscopy solutions for the life sciences and materials research, and medical technology solutions for diagnostics and treatment in ophthalmology and microsurgery. The name ZEISS is also synonymous with the world’s leading lithography optics, which are used by the chip industry to manufacture semiconductor components. There is global demand for trendsetting ZEISS brand products such as eyeglass lenses, camera lenses and binoculars.

With a portfolio aligned with future growth areas like digitalization, healthcare and Smart Production and a strong brand, ZEISS is shaping the future of technology and constantly advancing the world of optics and related fields with its solutions. The company’s significant, sustainable investments in research and development lay the foundation for the success and continued expansion of ZEISS’ technology and market leadership. ZEISS invests 13 percent of its revenue in research and development – this high level of expenditure has a long tradition at ZEISS and is also an investment in the future.

With around 37,000 employees, ZEISS is active globally in almost 50 countries with around 30 production sites, 60 sales and service companies and 27 research and development facilities (status: 31 March 2022). Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. The Carl Zeiss Foundation, one of the largest foundations in Germany committed to the promotion of science, is the sole owner of the holding company, Carl Zeiss AG.

Further information at www.zeiss.com 

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Ultivue develops unique solutions for use in mIF applications, imaging, and spatial phenomics. Its proprietary InSituPlex® technology enabling improved signal to noise data is designed for fast and comprehensive exploration of biologically relevant targets, up to 12-plex, with same slide-H&E analysis in tissue samples combines the power of computational pathology & spatial biology to guide translational science in immuno-oncology.

ngTMA® supports research collaborators with an interdisciplinary approach to studying tumor biology and disease states. Services include scientific consulting and TMA design, digital slide annotation, automated tissue punching and documentation for quality control. The ngTMA® platform is embedded in an innovative research framework and as part of the Translational Research Unit (TRU), Institute of Pathology, University of Bern, with expertise in tissue-related technologies.

“We are thrilled to be partnering with ngTMA® to jointly empower biopharma customers with tissue multiplex services. In addition, our scientific collaboration will investigate the relevance of the tumor microenvironment by characterizing clinically well-annotated cohorts using Ultivue reagents at ngTMA,” said Florian Leiss, Ph.D. Vice President Product Strategy & Corporate Development at Ultivue.

“We are very excited to join forces with the Ultivue team and have their reagents in our pipeline in order to support translational research of our collaborators,” Said Paulina Brönnimann, PhD, Head of Translational Research Unit.

About the Translational Research Unit and ngTMA®

TRU is a core facility at the Institute of Pathology at the University of Bern, providing human and animal tissue-related services with expertise in histology, tissue visualization, digital pathology, image analysis and construction of next-generation Tissue Microarrays (learn more at here).

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Collaborative efforts will initially focus on the development of AI to enable improved understanding of the tumor microenvironment and support the interpretation of Ultivue’s novel multiplex immunofluorescence (mIF) immuno-oncology biomarker panels.

The Paige portfolio includes the Paige Platform, a comprehensive imaging solution composed of the FDA-cleared and CE-marked FullFocus™, an intuitive and responsive viewer for pathology scans that supports primary diagnosis together with a data management solution for storage of pathology scans. The fast, zero-footprint, scanner-agnostic viewer, storage capabilities and AI-based diagnostic software help pathologists review cases and support their overall workflow.

Ultivue, a leader in advancing precision medicine solutions by accelerating tissue biomarker discovery and validation, develops unique platform agnostic solutions for use in both mIF imaging and spatial phenomics. Its proprietary InSituPlex® technology, designed for fast and comprehensive exploration of biologically relevant targets, up to 12-plex, with same slide-H&E analysis in precious tissue samples combines the power of computational pathology & spatial biology to guide translational science in immuno-oncology.

“This collaboration with Paige is an exciting milestone for Ultivue as we consider the evolving impact of AI and deep learning tools on histopathological images in clinical settings,” said Jacques Corriveau, CEO, Ultivue. “Importantly, our aligned goals are to facilitate the decentralization and democratization of the generation and analysis of complex spatial data.”

“The combination of Ultivue’s robust biomarker detection capabilities and Paige’s AI-enabled computational pathology technology allows us to deliver new products that will elevate how immuno-oncology research is done today,” said David Klimstra, M.D., Founder and Chief Medical Officer at Paige. “By uniting two platform-agnostic technologies, we are well-positioned to enable broad adoption of our AI-powered biomarker imaging solutions.”

About Paige

Keen Eye is a health technology company based in Paris, aiming to bring AI into every research Paige was founded in 2017 by Thomas Fuchs, Dr.Sc., David Klimstra, M.D., and colleagues from Memorial Sloan Kettering Cancer Center (MSK). The company builds computational pathology products designed so patients and their care teams can make effective, more informed treatment decisions. With this new class of AI-based technologies positioned to drive the future of diagnostics, Paige created a platform to deliver this novel technology to pathologists to transform their workflow and increase diagnostic confidence and productivity. Paige’s products deliver insights to pathologists and oncologists so they can arrive efficiently at more precise diagnoses for patients. Paige is the first company to receive FDA approval for an AI-based digital pathology product. For additional information, please visit: paige.ai, Twitter and LinkedIn.

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Accepted abstracts during the AACR conference will feature new data from a streamlined pre-optimized protocol enabling mIF staining on mouse tissue for an improved workflow to investigate T-cell infiltration and additional analysis of the tumor immune microenvironment (TiME) to address the mechanisms of action of immune-related drugs in preclinical syngeneic or GEMM mouse models.

The company will also spotlight an early access program for mouse researchers interested in exploring the use of advanced pre-clinical tools to probe the dynamic nature of events occurring in the TiME. Additional abstracts feature the new flexible mIF assays (FlexVUE™ panels) for discerning relevant distributions of infiltrating immune cells in tumors coupled with UltiStacker® software for producing detailed spatial characterizations of specific cell phenotypes.

Further datasets showcase the integrated capabilities from Fluidigm and Visiopharm to demonstrate a unique tissue phenotyping workflow combining complementary methods that can unravel the complexity of the tumor microenvironment.

Ultivue’s newest workflow to be highlighted at this year’s AACR will be available through the Company’s CLIA services lab and features a multi-omics analysis that demonstrates the versatility of Ultivue’s InSituPlex® technology (ISP) through an integrated workflow for co-detection of protein and RNA on a single tissue section.

Ultivue will also host its 2nd annual Biomarker Insights Summit on April 8th, 2022, ahead of the annual AACR meeting. This symposium is designed to promote thought leadership and has been exclusively curated for those working towards the eradication of cancer via immuno-oncology approaches. Scientists from AstraZeneca, Takeda, Gilead, Merck, Bayer, and many more will be onsite to share successes and lessons learned to better inform therapeutic efforts and explore how innovative digital pathology insights can provide benefit to clinical trials. For more information, visit biomarkerinsightssummit.com.

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Ultivue develops unique solutions for use in mIF applications, imaging, and spatial phenomics. Its proprietary InSituPlex® technology enabling improved signal to noise data is designed for fast and comprehensive exploration of biologically relevant targets, up to 12-plex, with same slide-H&E analysis in tissue samples combines the power of computational pathology & spatial biology to guide translational science in immuno-oncology.

Ultivue recognizes the need for dedicated and custom AI models to analyze the complexity of mIF data at scale and to provide improved turn-around times and consistent readouts across large cohorts “We are looking forward to accelerating data generation for biopharma customers from mIF kits by partnering with Keen Eye. We can jointly support more scalable workflows which will allow us to meet increasing demand in clinical trials.” said Florian Leiss, Ph.D. Vice President Digital Health Strategies at Ultivue.

Keen Eye is an AI Platform company dedicated to deliver accurate, standardized, and undiscovered tissue insights in research and clinical development using Deep Learning histopathology digital image analysis. Its proprietary models dedicated for spatial exploration of tumor microenvironment give access to reliable tissue segmentation, biomarker quantification, cell population profiling, and morphological discovery.

Thanks to Ultivue’s pre-optimized assays, the high accuracy achieved for every biomarker will drastically reduce errors during quantification steps, as phenotypes combine several biomarkers. As Dr. Sylvain Berlemont, Keen Eye’s founder and CEO says, “We are thrilled to expand our application portfolio combined with best-in-class Ultivue mIF assays to biopharma companies and CROs. This partnership will undeniably support our customers to fully extend reproducibility and scalability throughout their clinical research.”

About Keen Eye

Keen Eye is a health technology company based in Paris, aiming to bring AI into every research laboratory, CRO and pharmaceutical company, for the benefit of biologists, pathologists, and patients. Keen Eye is building decision-support and GCLP-compliant image analysis solutions relying on Deep Learning technology through web-based platforms. Keen Eye strives to support the development of new therapies with better, faster, and accurate analytics. Learn more at keeneye.ai.

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at ultivue.com.

Ultivue, a leader in advancing precision medicine solutions by accelerating tissue biomarker discovery and validation, develops unique solutions for use in both multiplex immunofluorescence (mIF) imaging and spatial phenomics. Its proprietary InSituPlex® technology, designed for fast and comprehensive exploration of biologically relevant targets, up to 12-plex, with same slide-H&E analysis in precious tissue samples combines the power of computational pathology & spatial biology to guide translational science in immuno-oncology. “Our InSituPlex technology offers valuable profiling of the tissue and expands the depth of information possible from a single section that is complementary to the high-parameter capabilities offered by Sirona Dx. We believe this joint offering will now provide researchers a seamless workflow enabling a far more efficient biomarker discovery and drug development process.” said Mark Rees, Ph.D. Vice President Corporate Development at Ultivue.

Sirona Dx are original pioneers of spatial biology, having launched ultra-high parameter, multiplexed imaging services to Biopharma in 2018. Their technology agnostic, full service, spatial biology suite, contributed to their selection as a Top 10 CRO of 2021 by Medhealth Outlook.

“We are delighted to announce this partnership with Ultivue” said Andrew Brown, Ph.D. Chief Commercial Officer at Sirona Dx. “Since 2018, clients have relied on our leading expertise to develop and implement customized, high performance multiplexed imaging panels of up to 40 markers. Having cast a wide net to identify the most informative tissue biomarker signatures, we can now harness Ultivue’s powerful InSituPlex® technology to rapidly develop, robustly validated mid-plex panels of up to 12 markers enabling our clients to accelerate their drug development programs with transformative biomarker capabilities.

About Sirona Dx

Sirona Dx is a technical CRO, founded to accelerate the pace of immunotherapy and targeted therapy development. Bridging silos between diagnostics manufacturers and translational clinical research our laboratory offers specialized high complexity, single cell proteomics and genomics services supporting pharmaceutical companies with their drug discovery and development programs. Learn more at Sironadx.com.

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at Ultivue.com.

The companies have already been working together since early 2021 to adapt Aignostics’ client platform to support visualization and analysis regrading some of Ultivue’s products and services, as well as provisioning of results and corresponding reports. The resulting co-developed platform will now be made available to joint clients.  Additionally, proof of concept work conducted on the Ultivue 12-plex Immunophenotyping biomarker panel in over 1,000 clinical NSCLC cases has demonstrated encouraging results for the capacity of AI-based analysis of multiplexed images for more consistent and reproducible readouts at scale. These results will be published later this year and respective AI models made available via the platform.

The companies are now expanding their relationship under a co-marketing agreement to offer the multiplex immunofluorescence (mIF) platform to their respective biotech and pharma clients, initially for research use, with a GCP-compliant version to follow later this year. Moreover, Ultivue and Aignostics will offer AI-powered image analysis services within the platform via Aignostics “Explainable AI” approach for the consistent and precise analysis of mIF cohorts at scale, for both translational research and clinical trial services in Ultivue’s CLIA accredited clinical research laboratory.  “We are excited to extend our workflow offering to include mIF AI for highly automated image analysis by partnering with Aignostics” says Florian Leiss, VP Digital Health at Ultivue. “Improved viewing capabilities enable us to interactively explore the interplay of mIF-labeled cell populations in the histological context of same-slide H&E.”

“We believe that development of Ultivue’s assays with our AI-powered image analysis will create insights from data at scale that are unprecedented in spatial biology today. We are excited to start offering this approach to our clients for translational science and clinical trials” said Viktor Matyas, CEO of Aignostics.

Besides offering research and development services to its clients, Ultivue and Aignostics will also develop and jointly certify products for the standardized analysis of certain Ultivue products in prospective clinical trials, that will become available in the future and are aimed at paving the way for more widespread use of these technologies in both clinical trials and into clinical routine.

About Ultivue

Ultivue provides researchers and scientists in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions coupled with our scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at Ultivue.com.

About Aignostics

Aignostics, a Berlin based company with offices in the US, is a digital pathology company dedicated to novel precision diagnostics through the use of a proprietary “Explainable AI” platform in pre-clinical and translational research and clinical trials. The use of such technology is expected to be crucial to implementation of AI-powered algorithms in routine diagnostics in order to verify (explain) the model’s decision outputs. Additionally, through its close alignment to Charité and TU Berlin amongst other collaborators, only Aignostics offers the combination of data access, sample testing and pathology expertise to develop digital pathology algorithms spanning multi-modal biomarker assay detection systems such as H&E, IHC and mIF, amongst others.

Ultivue, a leader in advancing precision medicine and unique image analysis solutions by accelerating tissue biomarker discovery and validation develops unique assays for use in multiplex immunofluorescence imaging and analysis. Its proprietary InSituPlex® technology is designed for fast and comprehensive exploration of biologically relevant markers combined with same slide-H&E analysis in precious tissue samples.

“Ultivue’s move and significant expansion at Burlington Biocenter is a strong indication of the company’s continued growth and the unwavering demand from life sciences tenants in the market,” said Kevin Malloy. “Market conditions were extremely challenging during our search as a result of biotech tenants leasing space at record levels. We ultimately secured the ideal space for the company’s evolving laboratory and office needs.”

“Avison Young did an exceptional job strategically navigating a challenging market with limited inventory to procure a space that aligned with our research, development and growth needs,” said James (Bud) Drummey, Vice President of Product and Quality at Ultivue who lead the facility search efforts. “Burlington Biocenter’s cutting-edge, lab-ready facilities and prime suburban location provided the space and efficiency for us to maximize productivity while acquiring and retaining top talent.”

About Avison Young

Avison Young creates real economic, social and environmental value as a global real estate advisor, powered by people. As a private company, clients collaborate with an empowered partner who is invested in their success. Avison Young is a 2021 winner of the Canada’s Best Managed Companies Platinum Club designation, having retained its Best Managed designation for 10 consecutive years.
For more information, visit avisonyoung.com

About Ultivue

Ultivue provides pathologists, researchers and scientists with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex^® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions and scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. For more information, visit ultivue.com.

Ultivue’s President and Chief Executive Officer, Jacques Corriveau, and Chief Financial Offer, Richard C. Malabre, will present at 9:20 am ET on November 17. Interested parties may listen to the presentation using the following link:  Ultivue Stifel Presentation

“We look forward to meeting investors and sharing our vision for continued rapid growth and exciting new products. Ultivue is at the forefront of innovation for tissue-based assays providing critical insights to researchers and pathologists from precious samples” said Jacques Corriveau, President and CEO.

About Ultivue

Ultivue provides researchers in translational medicine with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions and scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. Learn more at Ultivue.com.

About Stifel

Stifel Financial Corp. (NYSE: SF) is a financial services holding company headquartered in St. Louis, Missouri, that conducts its banking, securities, and financial services business through several wholly owned subsidiaries. The Company’s broker-dealer affiliates provide securities brokerage, investment banking, trading, investment advisory, and related financial services to individual investors, professional money managers, businesses, and municipalities.

Stifel hosts several client conferences and events each year, attracting top institutional investors as well as leading companies in their sectors of focus.

Steve is a seasoned commercial executive with 25 years of experience building and leading high performing sales and marketing teams. Steve was most recently the Vice President, Commercial Development at Haematologic Technologies, a leading provider of products and analytical services to support the research, development, and commercialization of large molecule biotherapeutics. Prior to Haematologic Technologies, he held executive and senior level sales and marketing roles at several medical device firms including Bionique Testing labs, Rheonix Inc, Roche Tissue Diagnostic (formerly Ventana Medical Systems, Inc.), and Abbott Laboratories.

Steve holds a BS. Psychology from Arizona State University, and is a certified Medical Technologist, (MT, ASCP).

Steve joins Ultivue after a successful year of funding and looks to help strengthen its position as a market leader affording flexible options for multiplex immunofluorescence assays for digital pathology.

“This is a very exciting time to join the Ultivue team and accelerate the adoption of our technology by scientists seeking to illuminate the biology behind cancer and other diseases, and work with drug developers to help speed the progress of life saving therapeutics into the clinic. I’m thrilled to lead this team of deeply committed and talented individuals as we seek to broaden the commercialization of this ground-breaking technology”, said Pemberton.

“Ultivue’s rapid growth and product expansion is driven by our corporate culture and the inspiring team dynamics. We’re very pleased to have Steve join the team. His style and experience perfectly compliment our recipe for success” noted Jacques Corriveau, President and CEO.

About Ultivue

Ultivue provides researchers and scientists with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex^® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions and a scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. For more information, visit ultivue.com.

Ultivue                                                                              

Fenel Eloi is a highly seasoned life sciences executive experienced in leading the transformation of small and mid-size companies to large operating global organizations. Mr. Eloi served as the CFO and then COO at Cell Signaling Technology, a bio-reagents company, from 2005 to 2018, where he provided leadership in the transformation of the company to a global operation. He currently serves on the Board of Directors and chairs the audit committee of 908 Devices, Inc. (Nasdaq: MASS), a pioneer of purpose-built handheld and desktop mass spec devices for chemical and biomolecular analysis. He also serves on the board of directors of MitoTherapeutix, a privately held drug development biotech company. “I am very excited to join Ultivue and help them scale their operations to the next level. This is an exciting time for spatial biology and Ultivue has a great opportunity to rapidly grow and favorably impact both their customers’ search for improved cancer treatments and patients’ lives,” said Mr. Eloi.

Mary Pat Lancelotta is currently Vice President, Corporate Marketing and Communications at Adaptive Biotechnologies (Nasdaq: ADPT), a pioneer and leader in immune medicine. She is a seasoned healthcare strategist with a passion for precision medicine and brings over 20 years of business and strategy experience. Prior to Adaptive, Mary Pat led corporate and Product Marketing for Foundation Medicine, a molecular information company. Before joining Foundation Medicine, she led corporate strategic initiatives and strategic planning at Quest Diagnostics. Mary Pat holds an MBA with honors from Columbia Business School and a BS in Biochemistry from Boston College. She is also on the board of directors of Molecular Match, a clinical decision support company, and the TargetCancer Foundation. “I am delighted to join the Board of Ultivue and look forward to working with the management team and fellow Board members to help grow the business, especially in the area of artificial intelligence to support image analysis,” said Mary Pat Lancelotta. “As we look to the future, working with big pharma, CRO and academic medical center customers, Ultivue has a tremendous opportunity to expand the impact of spatial biology on patients’ lives.”

“It’s an exciting time at Ultivue,” noted Jacques Corriveau, President and CEO. “The combination of Mary Pat’s ability to drive innovative commercial strategy for a global market alongside Fenel’s experience enabling technology advancements within our partnership ecosystem will help our customers bring exciting new therapies to market and positively impact the drive toward personalized cancer treatment.”

Ultivue, a leader in advancing precision medicine solutions by accelerating tissue biomarker discovery and validation develops unique assays for use in multiplex immunofluorescence imaging and analysis. Its proprietary InSituPlex^® technology is designed for fast and comprehensive exploration of biologically-relevant markers combined with same slide-H&E analysis in precious tissue samples.

Fluidigm is a leader in high-parameter imaging for the clinical translational research and clinical testing markets. It’s Imaging Mass Cytometry™ (IMC™) technology is designed for highly multiplexed targeted interrogation of tissue sections for 40 or more protein markers in one scan, with distinct non-overlapping signals from element-labeled antibodies detected simultaneously for each sub-micrometer pixel.   

The collaboration provides reseachers with end-to-end service capability for clinical and translational work. For example, InSituPlex technology is well suited to identify regions of interest that may require downstream, deep profiling with IMC™. Customer access to both technologies can improve the efficiency of drug discovery programs and, in translational research, enable patient stratification to triage cases that require further investigation.

“Imaging Mass Cytometry has become integral to the clinical translational research and clinical testing markets,” said Chris Linthwaite, Fluidigm President and CEO. “Through Fluidigm Therapeutic Insights Services, we will offer our customers access to our technology as well as that of Ultivue, providing optimum imaging solutions for biomarker discovery and drug development.”

“Ultivue is at the forefront of innovation to provide unique biological insights for our customers,” said Mark Rees, Vice-President of Business Development at Ultivue. “Our InSituPlex^® technology offers valuable profiling of the tissue and expands the depth of information possible from a single section that is complementary to the high-parameter capabilities of Imaging Mass Cytometry. We believe this joint offering with Fluidigm will now provide researchers a seamless workflow enabling a far more efficient biomarker discovery and drug development process.”

About Fluidigm

Fluidigm Corporation (Nasdaq:FLDM) focuses on the most pressing needs in translational and clinical research, including cancer, immunology, and immunotherapy. Using proprietary CyTOF® and microfluidics technologies, we develop, manufacture, and market multi-omic solutions to drive meaningful insights in health and disease, identify biomarkers to inform decisions, and accelerate the development of more effective therapies. Our customers are leading academic, government, pharmaceutical, biotechnology, plant and animal research, and clinical laboratories worldwide. Together with them, we strive to increase the quality of life for all.

Fluidigm, the Fluidigm logo, and CyTOF are trademarks and/or registered trademarks of Fluidigm Corporation in the United States and/or other countries. All other trademarks are the sole property of their respective owners. For Research Use Only. Not for use in diagnostic procedures. For more information, visit fluidigm.com.

About Ultivue

Ultivue, Inc. provides researchers and scientists with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex^® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions and scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. For more information, visit ultivue.com.

CAMBRIDGE, MA – Ultivue, a leader in advancing precision medicine solutions through a unique approach that combines multiplex biomarker analysis with same slide traditional H&E for tissue phenotyping, today announced the completion of a $50 million Series D round of financing. New investors include Ally Bridge Group, Pura Vida Investments and Tao Capital Partners. Previous venture investors in Ultivue who also participated in the financing include ARCH Ventures, Northpond Ventures and Applied Ventures, LLC.

This additional funding will help Ultivue strengthen its position in the market, deliver innovative solutions to address the dynamic nature of tumor biology from precious tissue samples and to provide researchers and pathologists with the ability to fully realize the potential of tissue biomarkers within digital pathology workflows.

Anna Yaeger, President and Portfolio Manager commented, “Ally Bridge Group is excited to be long term partners with Ultivue. We believe the company’s differentiated kit-based approach to multiplex immunofluorescence is well positioned to capitalize on the spatial biology revolution and creates maximum flexibility to support academic, biopharma, and CRO customers.”

“What Ultivue has is remarkably capable. They provide fast, accurate, previously unattainable multiplexed protein marker information at high resolution and on existing hardware. It is going to be exciting to see a well-resourced, well led Ultivue offer great capabilities to the biotech and pharma oncology community,” said Keith Crandell, Co-founder & Managing Director from ARCH Ventures.

“Ultivue is driving to make immunotherapy a reality for every patient that needs it with leading technology that enables advanced exploration and interrogation of tissue samples for precision medicine research. We’re proud to continue supporting the Ultivue team,” said Adam Wieschhaus, Ph.D., CFA, Director at Northpond Ventures.

“We’re excited to welcome our newest investors, and greatly appreciate the support from our existing investment partners,” says Jacques Corriveau, President and CEO of Ultivue. “This funding will allow us to expand our commercial efforts while also increasing the scope of our research and development in order to remain at the forefront of innovation and provide biological insights for our customers as they work to address the challenge of therapeutic response rates in patients using immunotherapy.”

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