Presented at: AACR 2024
Relevant for
InSituPlex, mIF-H&E fusion
Description Discover a new workflow that enables you to effectively combine H&E staining with mIF InSituPlex® assays and avoid the heat-induced epitope retrieval (HIER) steps that are the root cause of altered H&E staining. We present data showing co-registration of H&E and mIF images with sub-micron accuracy, enabling highly accurate molecular characterization and cellular phenotyping.
Kevin Hwang, Grace Vezeau, Edyta Olejnik, Douglas Wood, Ruben Cardenes, Lauren Duro, Gourab Chatterjee, Je H. Lee
Presented at: AACR 2024
Relevant for
Spatial Image Analysis, Spatial Insights, STARVUE™, UltiAnalyzer.AI™
Description We present a highly scalable, cost-effective, and reliable AI workflow built with a combination of OMERO Plus, PathViewer, AWS SageMaker, and Ultivue software to efficiently manage mIF big data for digital pathology.
Ruben Cardenes, Erin Diel, Douglas Wood, Je Lee, Martin Schulze, Lorenz Rognoni
Presented at: AACR 2024
Relevant for
InSituPlex, OmniVUE™, U-VUE
Description Our poster presents a simple, rapid, and robust workflow for performing Ultivue InSituPlex® mIF assays with OmniVUE™ panels on the Parhelia Omni-Stainer™. Tight slide temperature control and lower volume reagent used by the Omni-Stainer™ supports consistent, high performance, high throughput whole slide multiplexed biomarker detection for translational and clinical studies.
Kevin Hwang, Laura Duro, Alex Veith, Nelson Wedin, Nikolay Samisik, Je H. Lee.
Presented at: AACR 2024
Relevant for
Spatial Image Analysis, STARVUE™, UltiAnalyzer.AI™
Description We introduce UltiAnalyzer.AI™, a software tool that integrates a set of artificial intelligence (AI) models designed for fully automatic, highly accurate, highly efficient, and fully scalable whole-slide mIF analysis. By utilizing the wide dynamic range of Ultivue’s InSituPlex® technology and cloud computing capabilities, this tool increases the robustness, reproducibility, and throughput of mIF analysis in digital pathology.
Ruben Cardenes, Douglas Wood, Martin Schulze, Je Lee, Lorenz Rognoni.
Relevant for
FlexVUE, InSituPlex
Description Our ebook describes the implementation and utility of our new pre-optimized flexible multiplexed immunofluorescence assays (FlexVUE panels) to provide the necessary relevant distribution of infiltrating immune cells in tumors. The approach describes how to quickly customize your immune profiling assay to discover the biology most relevant to your research question by starting with the Immuno8 FixVUE panel backbone and switch out up to 2 markers (from a pre-optimized and verified list) to create your own custom 8-plex panel that identifies the immune cell subsets you need to find.
Relevant for
Collaboration, InSituPlex, OmniVUE (formerly FixVUE), OmniVUE (formerly FlexVUE)
Description Developing a multiplex immunofluorescence assay for the in depth characterization of activatedT cells in tumor tissue samples.
Presented at: ASCO 2022
Relevant for
Collaboration, FixVUE, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry
Presented at: ASCO 2022
Relevant for
FixVUE, InSituPlex, RNA scope
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry
Presented at: ASCO 2022
Relevant for
FixVUE, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry
Presented at: ASCO 2022
Relevant for
FlexVUE, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry
Presented at: ASCO 2022
Relevant for
Collaboration, FixVUE, Imaging mass cytometry, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry
Senior Product Manager AI & Data Analytics
Relevant for
FlexVUE, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
Moritz will drill his way through whatever intellectual challenge you’ll put in front of him. He previously perforated biochemistry, image analysis, data science, immuno-oncology biomarkers, product management/ownership. He’ll condense the best of our ideas into a coherent roadmap. His product backlog will guide us towards our vision one step at a time.
PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.
Senior Manager, FAS, North America
Relevant for
FlexVUE, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.
Senior Scientists, Product Development
Relevant for
FlexVUE, InSituPlex
Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.
PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.
Relevant for
FixVUE, InSituPlex
Description Our ebook describes the implementation and utility of our new pre-optimized flexible multiplexed immunofluorescence assays (FlexVUE panels) to provide the necessary relevant distribution of infiltrating immune cells in tumors. The approach describes how to quickly customize your immune profiling assay to discover the biology most relevant to your research question by starting with the Immuno8 FixVUE panel backbone and switch out up to 2 markers (from a pre-optimized and verified list) to create your own custom 8-plex panel that identifies the immune cell subsets you need to find.
