Whole slide imaging
9248 A novel method to minimize HIER-induced alterations on H&E staining in an integrated mIF-H&E workflow
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poster

Presented at: AACR 2024

A novel method to minimize HIER-induced alterations on H&E staining in an integrated mIF-H&E workflow

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Relevant for

InSituPlex, mIF-H&E fusion

Description Discover a new workflow that enables you to effectively combine H&E staining with mIF InSituPlex® assays and avoid the heat-induced epitope retrieval (HIER) steps that are the root cause of altered H&E staining. We present data showing co-registration of H&E and mIF images with sub-micron accuracy, enabling highly accurate molecular characterization and cellular phenotyping.

Authors

Kevin Hwang, Grace Vezeau, Edyta Olejnik, Douglas Wood, Ruben Cardenes, Lauren Duro, Gourab Chatterjee, Je H. Lee

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Want to meet with us? Check out our upcoming events.

Categories: 9245 A workflow for cloud-based AI development of multiplex IF image analysis using the OMEROPlus platform
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Presented at: AACR 2024

A workflow for cloud-based AI development of multiplex IF image analysis using the OMEROPlus platform

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Relevant for

Spatial Image Analysis, Spatial Insights, STARVUE™, UltiAnalyzer.AI™

Description We present a highly scalable, cost-effective, and reliable AI workflow built with a combination of OMERO Plus, PathViewer, AWS SageMaker, and Ultivue software to efficiently manage mIF big data for digital pathology.

Authors

Ruben Cardenes, Erin Diel, Douglas Wood, Je Lee, Martin Schulze, Lorenz Rognoni

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Want to meet with us? Check out our upcoming events.

Categories: 9242 Low-cost, high-sensitivity InSituPlex® mIF assays on the Parhelia Omni-Stainer™
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poster

Presented at: AACR 2024

Low-cost, high-sensitivity InSituPlex® mIF assays on the Parhelia Omni-Stainer™

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Relevant for

InSituPlex, OmniVUE™, U-VUE

Description Our poster presents a simple, rapid, and robust workflow for performing Ultivue InSituPlex® mIF assays with OmniVUE panels on the Parhelia Omni-Stainer. Tight slide temperature control and lower volume reagent used by the Omni-Stainer supports consistent, high performance, high throughput whole slide multiplexed biomarker detection for translational and clinical studies.

Authors

Kevin Hwang, Laura Duro, Alex Veith, Nelson Wedin, Nikolay Samisik, Je H. Lee.

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Want to meet with us? Check out our upcoming events.

Categories: 9239 UltiAnalyzer.AI™: An automatic and robust AI-driven tool for the quantification of multipleximmunofluorescence whole slide images
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poster

Presented at: AACR 2024

UltiAnalyzer.AI™: An automatic and robust AI-driven tool for the quantification of multipleximmunofluorescence whole slide images

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Relevant for

Spatial Image Analysis, STARVUE™, UltiAnalyzer.AI™

Description We introduce UltiAnalyzer.AI, a software tool that integrates a set of artificial intelligence (AI) models designed for fully automatic, highly accurate, highly efficient, and fully scalable whole-slide mIF analysis. By utilizing the wide dynamic range of Ultivue’s InSituPlex® technology and cloud computing capabilities, this tool increases the robustness, reproducibility, and throughput of mIF analysis in digital pathology.

Authors

Ruben Cardenes, Douglas Wood, Martin Schulze, Je Lee, Lorenz Rognoni.

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Want to meet with us? Check out our upcoming events.

Categories: 5903 Development of specific multiplexed immunofluorescence immune assays to study mouse models of tumorigenesis
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Development of specific multiplexed immunofluorescence immune assays to study mouse models of tumorigenesis

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Relevant for

Collaboration, InSituPlex, OmniVUE (formerly FixVUE), OmniVUE (formerly FlexVUE)

Description Developing a multiplex immunofluorescence assay for the in depth characterization of activatedT cells in tumor tissue samples.

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Want to meet with us? Check out our upcoming events.

Categories: 5869 Analysis of macrophages to the overall PD-L1 microenvironment using TMAs and InSituPlex
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Presented at: ASCO 2022

Analysis of macrophages to the overall PD-L1 microenvironment using TMAs and InSituPlex

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Relevant for

Collaboration, FixVUE, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

Authors

Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry

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Want to meet with us? Check out our upcoming events.

Categories: 5829 Improved Understanding of the Biology and Pathophysiology of the TME in PDAC Samples Revealed by Both InSituPlex and Imaging Mass Cytometry
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poster

Presented at: ASCO 2022

Improved Understanding of the Biology and Pathophysiology of the TME in PDAC Samples Revealed by Both InSituPlex and Imaging Mass Cytometry

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Relevant for

Collaboration, FixVUE, Imaging mass cytometry, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

Authors

Marie Cumberbatch, Douglas Wood, Gourab Chatterjee, Christopher Womack, Milan Bhagat, Lorcan Sherry

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5796 Introduction to Ultivue’s capabilities for immuno-oncology biomarker programs
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webinar
Moritz Widmaier, PhD; Branden Hopkinson, PhD

Senior Product Manager AI & Data Analytics

Introduction to Ultivue’s capabilities for immuno-oncology biomarker programs

Length: 20 minutes

Relevant for

FlexVUE, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

Meet the hosts

Moritz will drill his way through whatever intellectual challenge you’ll put in front of him. He previously perforated biochemistry, image analysis, data science, immuno-oncology biomarkers, product management/ownership. He’ll condense the best of our ideas into a coherent roadmap. His product backlog will guide us towards our vision one step at a time.

Author
Moritz Widmaier, PhD

Senior Product Manager AI & Data Analytics

PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.

Author
Branden Hopkinson, PhD
Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5788 Gaining key phenotypic data from the tumor microenvironment using 8-plex immunofluorescence staining and image analysis
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webinar
Angela Vasaturo, PhD; Lorcan Sherry, PhD

Associate Director, Scientific Affairs Ultivue; Chief Science Officer, OracleBio

Gaining key phenotypic data from the tumor microenvironment using 8-plex immunofluorescence staining and image analysis

Length: 60 minutes

Relevant for

FixVUE, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.

Author
Branden Hopkinson, PhD

Lorcan is an image analysis expert who previously spent 10 years in the pharmaceutical industry as a group leader (Organon, Schering-Plough, Merck & Co.). He led a group responsible for performing histology, immunohistochemistry / image analysis and he has considerable experience in developing translational biomarker strategies for projects across various therapeutic areas. He is a Prince 2® qualified project manager and has extensive experience in study management.

Author
Lorcan Sherry, PhD

Chief Science Officer, OracleBio

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Want to meet with us? Check out our upcoming events.

Categories: 5786 FlexVUE for research
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webinar
Bonnie Philips, PhD

Senior Manager, FAS, North America

FlexVUE for research

Length: 20 minutes

Relevant for

FlexVUE, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.

Author
Branden Hopkinson, PhD
Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5808 UltiStacker for mIF
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Doug Wood, PhD

Principal Software Engineer

UltiStacker for mIF

Length: 17 minutes

Relevant for

FixVUE, FlexVUE, InSituPlex, U-VUE

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.

Author
Branden Hopkinson, PhD
Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5784 FlexVUE for biomarker programs
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webinar
Angela Vasaturo, PhD

Associate Director Scientific Affairs

FlexVUE for biomarker programs

Length: 20 minutes

Relevant for

FlexVUE, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.

Author
Branden Hopkinson, PhD
Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5793 Introduction to FlexVUE
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webinar
Yvette Cajigas, ASCP

Senior Scientists, Product Development

Introduction to FlexVUE

Length: 11 minutes

Relevant for

FlexVUE, InSituPlex

Description Marie Cumberbatch from TriStar Technology Group presented a poster of collaborative work between TriStar, Ultivue, and OracleBio at American Society of Clinical Oncology (ASCO) 2022 over the weekend. The work involved multiplex IF staining and analysis of multi-tumor tissue microarrays, with this poster focusing on the contribution of macrophages to the overall tumor PD-L1 microenvironment across different cancer types. Such target prevalence data can help guide options for successful immunotherapy strategies.

PhD in Cellular and Genetic Medicine from the University of Copenhagen. Background in human embryonic stem cells and identification of cell of origin for various types of breast cancer. He joined Ultivue to help drive the message of just how powerful Ultivue’s mIF and same slide H&E are when combined with powerful artificial intelligence.

Author
Branden Hopkinson, PhD
Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

Categories: 5734 Overview of the differences between standard IHC and multiplexed immunofluoresence
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ebook

Overview of the differences between standard IHC and multiplexed immunofluoresence

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Relevant for

FixVUE, InSituPlex

Description Discover more about Multiplexed Immunofluorescence. Our new infographic discusses some of the differences of traditional IHC technology with our unique ISP technology enabling a comprehensive study of cellular composition, cellular functions, and cell-cell interaction, within the spatial context of the tumor.

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Want to meet with us? Check out our upcoming events.

Categories: 5880 Getting TiME on Your Side: Defining the future of precision medicine with advanced multiplexed immunofluorescence
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ebook

Getting TiME on Your Side: Defining the future of precision medicine with advanced multiplexed immunofluorescence

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Relevant for

FixVUE, InSituPlex, U-VUE

Description Discover more about Multiplexed Immunofluorescence. Our new infographic discusses some of the differences of traditional IHC technology with our unique ISP technology enabling a comprehensive study of cellular composition, cellular functions, and cell-cell interaction, within the spatial context of the tumor.

Want to meet with us? Check out our upcoming events.

Want to meet with us? Check out our upcoming events.

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